Ezequiel de Olaso (1932-1996)

Autopoiesis , adaptivity , teleology , agency EZEQUIEL

A proposal for the biological grounding of intrinsic teleology and sense-making through the theory of autopoiesis is critically evaluated. Autopoiesis provides a systemic language for speaking about intrinsic teleology but its original formulation needs to be elaborated further in order to explain sense-making. This is done by introducing adaptivity, a many-layered property that allows organism...

CONSELHO NACIONAL DE SAÚDE RESOLUÇÃO No 196 DE 10 DE OUTUBRO DE 1996

Robin Holliday 1932–2014

Robin Holliday When the founder of a field of investigation departs from our midst, there is the palpable feeling among his or her close associates that an era has come to an end. Such is the sense that the elders of the field of genetic recombination feel with the passing of Robin Holliday, whose very name is synonymous with the process. Hediedathis homeon theoutskirtsofSydney, Australia, on t...

Op-brhe130268 1931..1932

We have known about the strong association between AS and the HLA-B*27 (B*27) gene for the past 40 years; however, the mechanism with which only some allomorphs of the HLA-B27 molecule, as well as some other HLA class I molecules, are involved in the occurrence of SpAs is still unclear [1]. In this issue of Rheumatology, Cauli et al. [2] present data that may aid our understanding of this mecha...

Sense - making with a little help from my friends : Introducing Ezequiel Di Paolo and Hanne De Jaegher Tom

The work of Ezequiel Di Paolo and Hanne De Jaegher has helped to transform the enactive approach from relative obscurity into a hotly debated contender for the future science of social cognition and cognitive science more generally. In this short introduction I situate their contributions in what I see as important aspects of the bigger picture that is motivating and inspiring them as well as t...